What It Is:
Sucralfate is a gastroprotective medication used in cats to treat ulcers and erosions in the stomach and upper small intestine. It works by binding to ulcer sites and forming a protective barrier that shields damaged tissue from stomach acid and digestive enzymes, thereby promoting healing.
Sucralfate is available in oral tablet, liquid suspension, and powder forms and is prescribed by a veterinarian.
🐾 What It Treats
Sucralfate is used to manage:
- Gastric or duodenal ulcers
- Erosive gastritis
- Esophagitis from acid reflux
- Prevention of stress-related gastric injury in hospitalized cats
- Gastrointestinal bleeding associated with ulcers
It is often part of a multimodal gastrointestinal treatment plan alongside acid reducers and dietary management.
🧪 How It Works
Sucralfate is a complex of sucrose and aluminum hydroxide that:
- Adheres to ulcer and erosion sites forming a viscous protective layer
- Binds bile acids and pepsin reducing further mucosal damage
- Promotes local healing by concentrating growth factors at the injury site
It acts locally within the gastrointestinal tract and is minimally absorbed into the bloodstream.
🐾 Dosage and Administration
Key administration guidelines:
- Given on an empty stomach at least two hours before or after meals
- Typical dose is 0.5 to 1 gram per cat every six to eight hours or as prescribed
- Liquid suspension may be mixed with a small amount of water for ease of dosing
- Tablets may be crushed and mixed with a pill pocket if needed
Consistent timing relative to meals is essential for optimal mucosal protection.
🔍 Side Effects and Precautions
Sucralfate is generally well tolerated. Possible side effects include:
- Constipation from aluminum content
- Dry mouth or decreased appetite
- Rare aluminum toxicity in cats with severe kidney disease
Use with caution in cats with:
- Chronic kidney disease (risk of aluminum accumulation)
- Obstruction of the gastrointestinal tract
Ensure adequate hydration and monitor stool consistency when using.
🩺 Prognosis
When used correctly:
- Ulcer healing often begins within one week of treatment
- Full resolution may take two to four weeks depending on ulcer severity
- Combined therapy with acid reducers and dietary changes improves outcomes
Follow up evaluation by your veterinarian ensures complete healing and addresses underlying causes.
💡 Cat Owner Note
Sucralfate is a key tool for protecting your cat’s stomach from painful ulcers and promoting tissue repair. Remember to give it on an empty stomach and stick to the schedule. With consistent use and veterinary guidance your cat’s tummy can heal and get back to normal in no time.
❓ Frequently Asked Questions About Sucralfate for Cats
Can I give sucralfate with food?
No. It must be given on an empty stomach at least two hours before or after meals for proper adherence to ulcers.
How long does sucralfate take to work?
Cats may show improvement in one week, but full healing often requires two to four weeks of treatment.
Is sucralfate safe for long term use?
Long term use may risk aluminum accumulation in cats with kidney disease. Regular monitoring is advised.
Can I crush sucralfate tablets?
Yes. Tablets can be crushed and mixed with a small amount of water or a pill pocket for easier administration.
What if my cat vomits after the dose?
Contact your vet. They may adjust dosing or suggest transitioning to the liquid form.
Does sucralfate interact with other medications?
It can bind other oral drugs and reduce absorption. Give other medications at least two hours before or after sucralfate.