What It Is:
Prednisolone is a corticosteroid medication commonly prescribed for cats to reduce inflammation, suppress the immune system, and treat a wide range of conditions. It is one of the most frequently used drugs in feline medicine.
Prednisolone is the active form of prednisone, which is poorly converted by the feline liver. That is why cats are almost always prescribed prednisolone rather than prednisone.
🐾 Common Uses
Prednisolone is used to treat a variety of medical conditions in cats, including:
- Inflammatory Bowel Disease (IBD)
- Asthma or bronchitis
- Skin allergies or itching
- Autoimmune conditions
- Chronic inflammation
- Lymphoma or other cancers
- Immune mediated anemia or low platelet counts
- Stomatitis or severe gingivitis
- Arthritis or joint inflammation
It may also be used as part of palliative care to improve comfort and reduce symptoms in chronic disease.
🧪 How It Works
Prednisolone is a synthetic glucocorticoid, which mimics the natural hormones produced by the adrenal glands. It reduces inflammation by:
- Suppressing the immune system’s overactive response
- Decreasing the production of inflammatory chemicals
- Reducing swelling and pain
- Slowing the activity of certain immune cells
This makes it helpful for managing both inflammatory and immune mediated diseases.
💊 Dosage and Administration
Prednisolone is available in tablet, liquid, and injectable forms. The dose depends on your cat’s condition and how they respond to treatment.
Typical dosing guidelines:
- Anti inflammatory dose is lower and used for allergies or mild inflammation
- Immunosuppressive dose is higher and used for serious autoimmune conditions or cancer
- Frequency may range from daily to every other day depending on long term goals
Never adjust the dose or stop treatment suddenly without veterinary guidance.
⚠️ Potential Side Effects
Side effects depend on the dose and duration of treatment. Short term use is usually well tolerated. Long term use carries a higher risk of side effects such as:
- Increased thirst and urination
- Increased appetite
- Weight gain
- Behavior changes such as restlessness or agitation
- Thinning of the skin or fur loss
- Increased risk of infection
- Diabetes or elevated blood sugar
- Muscle weakness or lethargy
- Delayed wound healing
In rare cases, long term use can suppress the adrenal glands. Your vet may taper the dose gradually to prevent complications.
🩺 Monitoring and Safety
Your vet may recommend periodic bloodwork to check for side effects, especially if prednisolone is used long term. This may include:
- Blood glucose levels
- Liver enzymes
- Kidney function
- White blood cell counts
Cats with diabetes, kidney disease, or a history of infections may require closer monitoring.
💡 Cat Owner Note
Prednisolone can work wonders for cats with chronic inflammation or immune disease, but it is powerful medicine. Follow your vet’s instructions closely, and always ask before changing the dose or stopping treatment. When used correctly, it can dramatically improve your cat’s comfort and quality of life.
❓ Frequently Asked Questions About Prednisolone in Cats
Is prednisone the same as prednisolone?
No. Cats cannot convert prednisone effectively, so they are usually given prednisolone instead.
How long can a cat stay on prednisolone?
It depends on the condition. Some cats need it short term, others long term. Your vet will adjust the dose to balance benefits and risks.
Can I stop giving prednisolone suddenly?
No. Sudden withdrawal can cause serious side effects. Always taper the dose under veterinary supervision.
What if I miss a dose?
Give the missed dose as soon as you remember. If it is close to the next scheduled dose, skip the missed one. Do not double up.
Does prednisolone cause side effects in cats?
It can, especially with long term use. Common side effects include increased thirst, appetite, and urination. Your vet will monitor for complications.
Can prednisolone be used with other medications?
In many cases, yes, but it depends on the drug. Always tell your vet about all medications and supplements your cat is taking.