What It Is:
Orbax is the brand name for orbifloxacin, a fluoroquinolone antibiotic used in cats to treat bacterial infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and cell division, leading to bacterial death.
Orbax is available by prescription in tablet form and is approved for use in cats under veterinary supervision.
🐾 What It Treats
Orbax is prescribed for:
- Urinary tract infections (UTIs)
- Skin and soft tissue infections
- Respiratory infections
- Wound infections or abscesses
- Gastrointestinal infections caused by susceptible bacteria
- Ocular infections when compounded into ophthalmic formulations
It is often chosen when culture and sensitivity testing indicates fluoroquinolone susceptibility.
🧪 How It Works
Orbifloxacin interferes with bacterial DNA replication by:
- Blocking DNA gyrase which relieves DNA supercoiling
- Inhibiting topoisomerase IV which separates replicated DNA strands
These actions prevent bacterial reproduction and lead to cell death in both gram positive and gram negative organisms.
🐾 Dosage and Administration
Orbax dosing must be guided by a veterinarian. General guidelines:
- Given once daily by mouth, with or without food
- Dose based on body weight and infection type
- Tablets should be swallowed whole; do not crush or split unless directed
- Complete the full course, even if your cat improves early
Never use leftover or improperly stored antibiotic tablets.
🔍 Side Effects and Precautions
Orbifloxacin is generally well tolerated, but side effects may include:
- Vomiting or diarrhea
- Loss of appetite
- Lethargy
- Behavioral changes in rare cases
Use with caution or avoid in:
- Kittens under eight months due to potential cartilage effects
- Cats with known fluoroquinolone hypersensitivity
- Cats with seizure disorders (fluoroquinolones can lower seizure threshold)
Monitor your cat for any unusual signs and contact your vet if concerns arise.
🩺 Prognosis
When used appropriately:
- Most infections respond within three to five days
- Complete bacterial clearance depends on infection severity and treatment duration
- Follow-up cultures may be recommended in recurrent or severe cases
Adhering to the prescribed regimen helps prevent antibiotic resistance.
💡 Cat Owner Note
Orbax can be a powerful ally against stubborn infections, but fluoroquinolones must be used judiciously. Always follow your vet’s instructions, finish every dose, and never use it without a clear diagnosis. With proper use, Orbax helps your cat recover more quickly and comfortably.
❓ Frequently Asked Questions About Orbax for Cats
Can Orbax treat my cat’s cystitis?
Yes, if the bacterial strain is susceptible. Your vet may perform a culture to confirm.
Is Orbax safe for kittens?
Use with caution. It is not recommended for cats under eight months due to cartilage development concerns.
How quickly does Orbax work?
Many cats improve within three to five days, though the full course may run 7 to 14 days.
Can I split Orbax tablets?
Only if your vet specifically approves a modified dosing regimen. Crushing or splitting may alter absorption.
Does Orbax interact with other medications?
Fluoroquinolones can lower seizure threshold. Inform your vet about any other drugs or supplements your cat is taking.
What if my cat misses a dose?
Give it as soon as you remember unless it is close to the next scheduled dose. Do not double up.