What It Is:
Clindamycin is a prescription antibiotic commonly used in cats to treat bacterial infections involving the skin, mouth, bones, and internal organs. It belongs to the lincosamide class of antibiotics and works by inhibiting bacterial protein synthesis, which stops bacteria from growing and spreading.
Clindamycin is available in oral liquid, capsule, and injectable forms, and is often used when other antibiotics are not effective or when infections involve anaerobic bacteria.
🐾 What It Treats
Clindamycin is used to treat a variety of infections in cats, including:
- Dental infections such as tooth root abscesses or periodontal disease
- Bone infections (osteomyelitis)
- Skin wounds and abscesses
- Respiratory infections caused by susceptible bacteria
- Toxoplasmosis, especially when combined with other therapies
- Deep soft tissue infections and post surgical infections
It is often used off label, which is common and appropriate when guided by a veterinarian.
🧪 How It Works
Clindamycin stops bacteria from reproducing by blocking protein production inside the bacterial cell. It is bacteriostatic at low concentrations (slows bacterial growth), and bactericidal at higher concentrations (kills bacteria outright).
It is especially effective against anaerobic bacteria and gram positive cocci, including Staphylococcus and Streptococcus species.
🐾 Dosage and Administration
Clindamycin is typically given once or twice daily, depending on the formulation and condition being treated.
Important notes:
- Always follow the exact dose and schedule prescribed by your vet
- Liquid form may have a strong taste and is often easier to give if mixed with food
- Capsules should not be given dry, as they may irritate the throat or esophagus
- Complete the full course, even if your cat seems better
Never give leftover antibiotics or change the dose without consulting your vet.
🔍 Side Effects and Precautions
Clindamycin is generally well tolerated, but potential side effects include:
- Vomiting or diarrhea
- Loss of appetite
- Drooling or bad taste in the mouth
- Increased liver enzymes in rare cases
- Signs of gastrointestinal upset such as soft stool or cramping
Use with caution in cats with:
- Liver or kidney disease (may require dose adjustments)
- History of gastrointestinal issues
- Known sensitivity to lincosamide antibiotics
Clindamycin should not be combined with other antibiotics that work in opposing ways unless directed by your vet.
🩺 Prognosis
With proper use, clindamycin is highly effective:
- Most infections begin to improve within two to three days
- Full resolution depends on infection type and severity
- Completing the entire treatment course is essential to avoid relapse or resistance
If vomiting, diarrhea, or lack of appetite occurs, your vet may adjust the dosage or suggest giving the medication with food.
💡 Cat Owner Note
Clindamycin is one of those behind the scenes antibiotics that your vet may reach for when an infection gets deep, stubborn, or tricky, especially in the mouth or bone. Just follow the instructions, and don’t stop early. Even if your cat gives you the stink eye over the taste, this medicine does real work.
❓ Frequently Asked Questions About Clindamycin for Cats
Can I give my cat clindamycin prescribed for my dog?
No. Always consult your vet. Doses and formulations may differ, and inappropriate use can cause harm.
How quickly does clindamycin work in cats?
Many infections begin to improve within two to three days, but the full course should always be completed.
Can clindamycin upset my cat’s stomach?
Yes. Some cats experience nausea or diarrhea. Giving it with food may help reduce side effects.
Is clindamycin safe for long term use?
It can be, but long term use should be monitored closely with periodic checkups and lab tests.
What infections is clindamycin best for?
Clindamycin is especially useful for dental, bone, skin, and deep soft tissue infections.
Can I crush the capsule if my cat refuses it?
No. Crushing capsules may increase bitterness and cause drooling or vomiting. Ask your vet for a liquid version if needed.